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Scientific Research

The secret for best clinical practice

Knieband: Kniespecialist RPA Janssen is de deskundige in behandeling van knieband blessures. Osteotomie: informatie, klachten, diagnose en behandeling.
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Nieuwe publicatie

RPA janssen MD PhD Prof is memeber of the PaTIO study group. Recently, a publication has been...

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Two new publications

Recently 2 new publications have been accepted in peer reviewed journals. These...

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High systemic gentamycin levels and ototoxicity after implantation of gentamycin beads in a 70-year-old man-a case report

High systemic gentamycin levels and ototoxicity after implantation of gentamycin beads in a 70-year-old man-a case report

Klaver de PA, Koning J, Janssen RPA, Derijks LJ
Acta Orthopaedica 2009;80(6):734-6

Gentamycin beads are used for muskuloskeletal infections. Gentamycin is released gradually from the beads, and high gentamycin concentrations are achieved only locally. Side effects of gentamycin are rarely to be expected with gentamycin beads since only low amounts of gentamycin are released from the beads, resulting in extremely low serum concentrations of the antibiotic. Only one case of prolonged raised gentamycin serum levels from gentamycin beads has been described to date, but no adverse affects were reported in that case. We present another case with ototoxicity.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823315/?tool=pubmed


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RPA Janssen, MD PhD Prof
Orthopaedic Surgeon
Orthopaedic Associates Eindhoven Greater Area
Orthopedic Center Máxima
Máxima Medical Center (MMC)

Visiting adress MMC Eindhoven:
Ds. Th. Fliednerstraat 1
Ingang Zuid
5631 BM  Eindhoven
The Netherlands 
(outpatient clinic and surgery)

Visiting adress MMC Veldhoven:
De Run 4600
5504 DB  Veldhoven
The Netherlands
(Outpatient clinic)

Mail adress:
Postbus 90052
5600 PD  Eindhoven
The Netherlands

Tel. 0031 (0)40 88 88 600
(Call center Orthopedie)

Fax: 0031 (0)40 88 85 938
www.rpajanssen.com 

Links:
KneeGuru
Orthopaedic Associates Eindhoven Greater Area
Máxima Medical Center
Eindhoven University of Technology
Fontys University of Applied Sciences
 

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